Reduced Opioid-Related Adverse Events (ORADEs) in Chiropractic Spinal Manipulation (CSM) Patients: A Breakthrough Study

Chiropractic Spinal Manipulation Linked to Lower Risk of Opioid-Related Adverse Events: What This Means for Patients in Porter Ranch, CA
At Soft Touch Chiropractic in Porter Ranch, CA, we are committed to providing drug-free, evidence-based care for pain relief and long-term wellness. A new study published in PLOS One strengthens the case for chiropractic spinal manipulation (CSM) as a safer, more effective alternative to traditional pain management strategies involving opioids.
New Study Shows 71% Lower Risk of Opioid-Related Adverse EventsIn this retrospective cohort study, researchers examined data from the TriNetX Diamond Network, including over 744,000 patients. They discovered that patients receiving chiropractic spinal manipulation were 71% less likely to experience opioid-related adverse events (ORADEs) within one year compared to those receiving usual medical care. Specifically, just 0.09% of patients in the CSM group experienced an ORADE, versus 0.30% in the usual care group—a statistically significant difference.
Additionally, patients in the CSM cohort were 32% less likely to be prescribed oral opioids, reinforcing what many patients in Porter Ranch, CA already know: chiropractic care offers effective, non-addictive pain relief.
Chiropractic Care at Soft Touch Chiropractic in Porter Ranch, CAAt Soft Touch Chiropractic, we focus on gentle, non-invasive techniques to treat musculoskeletal conditions, including sciatica, neck pain, and lower back pain. Our team uses chiropractic spinal manipulation as part of a multimodal approach, helping reduce the need for opioid medications and their potential risks.
The study’s lead author, Dr. Robert Trager, DC, noted that while previous research linked chiropractic care to reduced opioid use, this is the first large-scale study to show a significant reduction in opioid-related adverse events.
“This adds an important layer of clinical relevance,” Trager said.
Dr. Roshini Srinivasan, MD, co-author and resident at Duke University Hospital, added, “Chiropractic spinal manipulation is not only effective—it could be life-saving.”
A Safer Path Forward for Pain ReliefThe study excluded patients with prior ORADEs and opioid use disorder and used rigorous propensity score matching to balance demographics and clinical variables. While limitations such as unmeasured confounding exist (common to retrospective studies), the findings support current clinical guidelines that recommend spinal manipulation as part of conservative care for pain conditions like sciatica.
For patients in Porter Ranch, CA, this study reinforces the importance of choosing non-pharmacological options like Soft Touch Chiropractic for managing chronic pain safely and effectively.
University Hospitals Cleveland Medical Center Jan 29 2025

Ready to Experience Drug-Free Pain Relief? If you're looking for a safer alternative to opioids for pain management, contact Soft Touch Chiropractic in Porter Ranch, CA today. We’ll help you explore personalized, effective treatments that prioritize your health and long-term wellness.
Call us or book your appointment online today. Your body deserves better—and safer—care.

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Dr. Masoud Shamaeizadeh, DC, is a seasoned chiropractor practicing at Soft Touch Chiropractic in Porter Ranch, CA. With a career spanning over three decades, Dr. Shamaeizadeh has been dedicated to enhancing patient health through non-invasive, drug-free treatments. He earned his chiropractic degree from Cleveland College of Chiropractic and established Soft Touch Wellness Center in 2002. 
At Soft Touch Chiropractic, Dr. Shamaeizadeh offers personalized care plans that may include spinal adjustments, acupuncture, and physiotherapy. The clinic emphasizes a holistic approach to health, aiming to restore the body's natural healing abilities without the use of toxic drugs or invasive procedures. 
The clinic is located at 11145 Tampa Ave, Suite 14A, Porter Ranch, CA 91326. For appointments or inquiries, you can contact the office at (818) 831-0100. porterranchchiropractic.net+4porterranchchiropractic.net+4porterranchchiropractic.net+4FindaTopDoc+9Vitals+9porterranchchiropractic.net+9
Dr. Shamaeizadeh is also known for his community involvement, sharing his expertise through seminars and speaking engagements on topics such as nutrition, hormonal balance, and detoxification. porterranchchiropractic.net
If you're seeking chiropractic care in the Porter Ranch area, Dr. Masoud Shamaeizadeh's extensive experience and holistic approach make Soft Touch Chiropractic a noteworthy option.