Pregnenolone Benefits: The Mother of All Hormones for Anti-Aging, Stress Relief, and Brain Health

Pregnenolone: The “Mother of All Hormones”
Presented by Dr. Masoud Shamaeizadeh, Soft Touch Chiropractic

Pregnenolone is a natural hormone made in the adrenal glands and brain. It’s called the “mother of all hormones” because it’s the starting point for DHEA, testosterone, estrogen, and progesterone.

Levels peak around age 30, then steadily drop with age, making pregnenolone a youth-associated hormone linked to energy, memory, and stress resilience.



​Quick Benefits of Pregnenolone

• Balances hormones: Supports DHEA and testosterone production
• Boosts brain health: Improves memory, focus, and sleep quality
• Protects against stress: Counters cortisol and supports calmness
• Supports metabolism: Regulates blood sugar, cholesterol, and weight
• Promotes longevity: Anti-aging effects for bones, heart, and cells

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Anti-Aging Power

• Converts into DHEA, which supports energy, bone density, and blood sugar balance
• Helps produce testosterone, vital for heart, muscle, and thyroid health
• Protects the heart with antioxidant and anti-inflammatory effects
• Promotes healthy cholesterol balance

Stress Protection
Aging = more cortisol (stress hormone) + less protective hormones
Pregnenolone helps:

• Block cortisol’s damaging effects (weight gain, blood pressure, muscle loss)
• Convert to allopregnanolone, a calming brain chemical that reduces anxiety
• Support resilience and emotional stability

Brain Benefits
Pregnenolone is naturally concentrated in the brain. Research shows it can:

• Improve mood and help with depression symptoms
• Enhance deep sleep (slow-wave sleep for repair & immunity)
• Protect against toxins and inflammation
• Support memory and learning through healthy brain signaling

Should You Supplement? Pregnenolone is available as a supplement, but everyone’s hormone needs are unique. Blood testing and professional guidance are recommended for safe and effective use.

The Bottom Line
Pregnenolone is more than just a hormone; it’s a key to balance, brain health, stress resilience, and anti-aging. Supporting your levels can help you feel sharper, calmer, and more youthful as you age.

At Soft Touch Chiropractic, Dr. Masoud Shamaeizadeh helps patients restore balance naturally through chiropractic care, stress reduction strategies, and holistic wellness guidance.

Schedule your visit today and discover how hormone support and chiropractic adjustments can work together to help you age stronger, think clearer, and live better!
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Masoud Shamaeizadeh
11145Tampa Ave #14A
Northridge, CA 91326
818-831-0100

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A study published in Neuropsychopharmacology
study in Brain Research 
https://pmc.ncbi.nlm.nih.gov/articles/PMC6433066
https://pubmed.ncbi.nlm.nih.gov/31525393